goat anti mouse il 17c polyclonal ab (R&D Systems)
Structured Review

Goat Anti Mouse Il 17c Polyclonal Ab, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/goat+anti+mouse+il+17c+polyclonal+ab/pmc06200819-239-4-10?v=R%26D+Systems
Average 90 stars, based on 2 article reviews
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1) Product Images from "The roles of IL-17C in T cell-dependent and -independent inflammatory diseases"
Article Title: The roles of IL-17C in T cell-dependent and -independent inflammatory diseases
Journal: Scientific Reports
doi: 10.1038/s41598-018-34054-x
Figure Legend Snippet: Generation of Il17c −/− mice. ( a ) IL-17C gene targeting strategy. The region of the Il17c gene containing from exon 1 to exon 3 was replaced with a cassette containing a neomycin resistance gene ( Neo r ), flanked by loxP sequences. ( b ) Expression of Il17c mRNA in various tissues from wild-type (n = 3) and Il17c −/− (n = 3) mice, determined by qPCR. The data show the mean + SEM.
Techniques Used: Expressing
Figure Legend Snippet: Strong resistance of Il17c −/− mice to T cell-independent endotoxin shock. Female mice were injected intraperitoneally with LPS. After LPS injection, survival was monitored, and peritoneal fluids were collected at the indicated points. ( a ) Survival of wild-type (n = 47) and Il17c −/− (n = 46) mice after LPS injection. ***p < 0.001. ( b ) The concentrations of IL-17C, IL-1β, IL-6, IL-17A and TNF in peritoneal lavage fluids from wild-type mice (0 h, n = 5; 3 h, n = 5; 6 h, n = 6) and Il17c −/− mice (0 h, n = 5; 3 h, n = 5; 6 h, n = 6) were measured by ELISA. The data show the mean + SEM. *p < 0.05: wild-type mice vs. Il17c −/− mice. ( c ) Peritoneal F4/80 − and F4/80 + cells were stimulated with LPS for the indicated times. The expression levels of Il17c and Il17re mRNAs in the cells were determined by quantitative PCR. The data show the mean + SEM (n = 3). ( d ) The expression levels of Il17c , Il17re , Il1b , Il6 , Il17a and Tnfa mRNAs in the tissues and peritoneal lavage fluid cells from wild-type mice at 0, 3 and 6 h after LPS injection were determined by quantitative PCR. The data show the mean + SEM (n = 5). *p < 0.05, **p < 0.01 and ***p < 0.001 vs 0 h ( c , d ).
Techniques Used: Injection, Enzyme-linked Immunosorbent Assay, Expressing, Real-time Polymerase Chain Reaction